122 research outputs found

    Finite-time stability analysis of fractional order time-delay systems: Gronwall's approach

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    In this paper, a stability test procedure is proposed for linear nonhomogeneous fractional order systems with a pure time delay. Some basic results from the area of finite time and practical stability are extended to linear, continuous, fractional order time-delay systems given in state-space form. Sufficient conditions of this kind of stability are derived for particular class of fractional time-delay systems. A numerical example is given to illustrate the validity of the proposed procedure

    REALIZATION OF DISTRIBUTED MEDICAL DATA REPOSITORY IN AN ENVIRONMENT WITH HETEROGENOUS MIS

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    The introduction of centralized registers of medical data after a long time from the implementation of medical information systems and their long-term daily operation is a very challenging and demanding process. In this paper, three ways for the realization of centralized repositories of medical data are considered, and on that occasion, the advantages and limitations of these solutions are emphasized. Due to the heterogeneity of medical information systems in terms of technologies used and implementation, the construction of a distributed centralized national register of medical data emerges as a good solution. A proposal of architecture for the realization of the distributed central republic register of medical data is given. As an example of the proposed solution, the realized collaboration of the central republic radiological information system and its implementation with the medical information system MEDIS.NET is presented

    Pravne osnove učeŔća policije u vanrednim situacijama

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    Police officers who belong to the General Police Directorate of Republic of Serbia, in addition to the numerous powers and tasks they perform, based on the Law on Police, have the obligation to participate in protection and rescue operations. Besides the aforementioned law, the police are recognized as a part of the protection and rescue forces by the Law on Risk Reduction and Emergency Management. The role of the police in emergency situations is very important, and the scope of work of the police officers is expanding over time and becoming more and more diverse, and thus more complex. The police engages in the execution of tasks aimed at the security protection of citizensā€™ property and lives, such as rescue and evacuation from endangered areas, providing first aid, delivery of food, medicine, etc.Policijski službenici, koji pripadaju Direkciji policije Republike Srbije, pored brojnih ovlaŔćenja i poslova koje obavljaju, na osnovu Zakona o policiji, imaju obavezu da učestvuju i u poslovima zaÅ”tite i spasavanja. Pored navedenog Zakona, policija je prepoznata kao deo snaga zaÅ”tite i spasavanja i Zakonom o smanjenju rizika i upravljanju vanrednim situacijama. Uloga policije u vanrednim situacijama je veoma značajna, a obuhvat delokruga rada policijskih službenika se vremenom proÅ”iruje i postaje sve raznovrsniji, a time i kompleksniji. Policija se angažuje za izvrÅ”avanje zadataka usmerenih na bezbednosnu zaÅ”titu imovine i života građana poput spasavanja i evaluacije iz ugroženih područja, pružanje prve pomoći, dostavu hrane, lekova i sl

    Colloid electrohydrodynamics

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    This brief extracted review presents the recent development in basic and applied science and engineering of finely dispersed particles and related systems in general, but more profound and in-depth treatise are related to the liquid-liquid finely dispersed systems, i.e. emulsions and double emulsions. Twenty-five years ago, the idea, at first very fogy, came out from the pilot plant experiments related to the extraction Of uranium from wet phosphoric acid. In particular the solution of the entrainment problems, breaking of emulsions/double emulsions, as the succession of the extraction and stripping operations/processes, was performed In this pilot plant, secondary liquid-liquid phase separation loop was designed and carried out. The loop consisted of a lamellar coalescer and four flotation cells in series. Central equipment in the loop, relevant to this investigation, was the lamellar coalescer. The phase separation in this equipment is based on the action of external forces of mechanical and/or electrical origin, while adhesive processes at the inclined filling plates occur. Since many of related processes, e.g. adhesive processes, rupture processes and coalescence, were not very well understood, deeper research of these events and phenomena was a real scientific challenge

    Forensics of Features in the Spectra of Biological Signals

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    Semantics of spectroscopy of biological signals and criteria of semantic stability are the initial issues in this article. Motivated with some semantic confusion related to our cooperation and elsewhere, we are investigating the circumstances in which spectroscopic features have direct meaning and when that is questioned. Two problems arise immediately: what are additional ways in signal analysis through spectroscopy and generalizations and how can we learn more on the processes investigated. Our aim is to enrich the available methods and tools providing researchers with additional ways in detailed analysis of biological signal spectra and help to overcome some of difficulties. We show some of our work in signal spectroscopy, aiming to signal forensics and to uncover more details in the investigated signals, discuss invariants of involved operators, addressing the WYSIWYG - ā€œwhat you see is what you getā€ method property. Ziggurat like structures of spectral features, parallel multiple resolution spectroscopy, application of image processing tools on spectral features and second order spectroscopy take place in the investigation of fine spectrogram feature details. Automatized feature detection and comparisons techniques, are used. These set of procedures represent our improvements and contribution to this important method for analysis of biological signals, illustrated on the examples from our practice, processed with our implementations

    Some details on the method for measuring activity changes of neuronal populations

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    Simple, complex action potentials (AP) and interspike recorded background activity (RBA) were detected and extracted from 12 rat cerebellar cortical recordings. For each recording, an averaged simple action potential (SAP) was formed. Fourier amplitude spectra of SAP and RBA were similar in all recordings. For one of the recordings, a series of RBA simulations (SBA) was generated, superimposing random SAPs, varying the superposition frequency (fsup). Average Fourier amplitude, Amp(SBA), was calculated, in order to use Amp(SBA)=f(fsup) as a calibration line for reading fsup of RBA, which is a measure of the population activity. A probability distribution for SAP intensities was derived and a family of calibration lines constructed. As all lines were linear and parallel (slope S) in log-log plots, a population activity change could be calculated as fsup2/fsup1=[Amp2(RBA)/Amp(RBA)]1/S.Jednostavni, složeni akcioni potencijali (AR) i međuspajkovna osnovna aktivnost (MOA) detektovani su i izdvojeni iz 12 registrovanih signala kore malog mozga pacova. Za svaku registraciju, formiran je usrednjeni jednostavni AR (JAR). Spektri Furijeovih amplituda JAR i MOA signala bili su slični kod svih registracija. Za jednu od registracija, superponiranjem slučajnih usrednjenih jednostavnih akcionih potencijala formiran je niz simulacija međuspajkovne osnovne aktivnosti (SOA), pri čemu je varirana frekvencija superpozicije (fsup). Izračunavana je srednja Furijeova amplituda, Amp(SBA), u cilju koriŔćenja Amp(SBA)=f(fsup) kao kalibracione linije za očitavanje fsup od MOA, Å”to je mera za aktivnost populacije. Izvedena je raspodela verovatnoća za intenzitete JAR, pomoću koje je konstruisana familija kalibracionih linija. Kako su sve linije linearne i paralelne u log-log dijagramu, sa nagibom S, promena aktivnosti populacije može se izračunati kao fsup2/fsup1 =[Amp2(RBA)/Amp(RBA)]1/S.nul

    Uloga statističkih evaluatora i njihova primena kod analize tačnosti segmentiranih medicinskih snimaka

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    Neosporna je uloga i primena medicinskih snimaka u danaÅ”njoj oblasti medicine i stomatologije jer je na osnovu njih moguće izvrÅ”iti tačnu dijagnozu kod pacijenata. Međutim, primenom savremenih uređaja za akviziciju ovih snimaka, mogu se pojaviti određene anomalije u vidu artefakata na medicinskim simcima. Uporedo sa ovim problemom, razvijale su se i metode za obradu medicinskih snimaka. Kako bi se verifikovala njihova primena i dokazala uspeÅ”nost njihove primene, tako su se razvijale i mnoge metode i evaluatori za analizu i statističku obradu ovih snimaka. U ovom radu biće prikazane neke od najčeŔće primenjivanih statističkih metoda i evaluatora koji se koriste kod analize medicinskih snimaka

    Distribucija organohlornih pesticida i polihlorovanih bifenila u dve vrste riba iz Dunava

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    The distribution and contents of organochlorine pesticides (OCPs) and congeners of polychlorinated biphenyls (PCBs) were analyzed in Bream (Blicca bjoerkna) and Barbel (Barbus barbus) from the Danube River, near Batajnica. The analysed compounds were 16 OCPs (Ī±-Hexachlorocyclohexane (Ī±-HCH), Ī²-Hexachlorocyclohexane (Ī²-HCH), Hexachlorobenzene (HCB), Ī³-Hexachlorocyclohexane (Ī³-HCH), Ī“-Hexachlorocyclohexane (Ī“-HCH), Heptachlor, Aldrin, cis-Heptachloroepoxide (cis-HCE), trans-Heptachloroepoxide (trans-HCE), Ī³-Chlordane, p,p'-Dichlorodiphenyldichloroethylene (p,p'-DDE), Ī±-Chlordane, Dieldrin, Endrin, p,p'-Dichlorodiphenyldichloroethane (p,p'-DDD), p,p'-Dichlorodiphenyltri-chloroethane (p,p'-DDT)) and 7 PCB congeners (IUPAC numbers 28, 52, 101, 138, 153, 180, 118). Determination and quantification of OCPs and PCBs were performed by a GC-ECD method. The proximate composition of fish fillets was determined by applying standard SRPS ISO methods. The statistically significant difference (p lt 0.05) was found between the OCPs content in Bream and Barbel, as well as between PCBs content in the analyzed fish filets. Among all analyzed pesticides, both fish contained the highest amounts of Ī£DDT (expressed as sum of p,p'-DDT + p,p'-DDE + p,p'-DDD), (13.8 ng/g fish - Bream, 2.6 ng/g fish - Barbel). The sum of PCB congeners in Bream filets (40.8 ng/g fish) was significantly higher than in Barbel filets (7.2 ng/g fish). Results of Student's t-test (p = 0.05) showed the differences in the content of lipids, moisture, ash and calculated energy value between the analyzed fish filets. Four times higher fat content in Bream (4.25%) than in Barbel (1.07%) is one of the main reasons for higher content of OCPs and PCBs in Bream compared to Barbel, which were taken from the same location (The Danube River, Batajnica).U ovom radu prikazana je distribucija i sadržaj organohlornih pesticida (organochlorine pesticides, OCP) i polihlorovanih bifenila (polychlorinated biphenyls, PCB) u ribama krupatici (Blicca bjoerkna) i mreni (Barbus barbus) iz Dunava u blizini Batajnice. Ispitano je 16 organohlornih pesticida i 7 kongenera polihlorovanih bifenila. Anlizirana su sledeća jedinjenja: Ī±-heksahlorocikloheksan (Ī±-HCH), Ī²-heksahlorocikloheksan (Ī²-HCH), heksahlorobenzen (HCB), Ī³-heksahlorocikloheksan (Ī³-HCH), Ī“-heksahlorocikloheksan (Ī“-HCH), heptahlor, aldrin, cis-heptahloroepoksid (cis-HCE), trans-heptahloroepoksid (trans-HCE), Ī³-hlordan, Ī±-hlordan, p,p'-dihlorodifenildihloroetilen (p,p'-DDE), dieldrin, endrin, p,p'-dihlorodifenildihloroetan (p,p'-DDD) i p,p'- dihlorodifeniltrihloroetan (p,p'-DDT) i PCB kongeneri označeni IUPAC brojevima 28, 52, 101, 138, 153, 180 i 118. Kvalitativna i kvanitativna ispitivanja ovih jedinjenja rađena su GC-ECD metodom. Sadržaj proteina, lipida, vlage i pepela u filetima riba određen je koriŔćenjem standardnih SRPS ISO metoda. Utvrđena je statistički značajna razlika (p lt 0,05) između sadržaja organohlornih pesticida u krupatici i mreni, kao i između sadržaja polihlorovanih bifenila u ispitanim ribama. Najveći sadržaj među ispitivanim organohlornim pesticidima, u obe vrste ribe utvrđen je za Ī£DDT (pp'-DDT + pp'-DDE + pp'-DDD), (13,8 ng/g ribe - krupatica, 2,6 ng/g ribe - mrena). Ukupan sadržaj PCB jedinjenja u filetima krupatice (40,8 ng/g ribe) bio je značajno veći nego u filetima mrene (7,2 ng/g ribe). Na osnovu rezultata Studentovog t-testa (p = 0,05) utvrđeno je da postoji statistički značajna razlika u sadržaju masti, vlage, pepela i izračunate energetske vrednosti između fileta ispitanih riba. Četiri puta veći sadržaj masti u filetima krupatice (4,25%) u odnosu na filete mrene (1,07%) jedan je od glavih razloga većeg sadržaja organohlornih pesticida i polihlorovanih bifenila u krupatici nego u mreni, koje su uzete sa istog lokaliteta (Dunav, Batajnica)

    Activity of antioxidative defense enzymes in the blood of patients with liver echinococcosis

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    Background/Aim. Chronic echinococcocal disease is the parasite human disease caused by the penetration of larval (asexual) stages of the canine tapeworm (Echinococcus granulosus) in the liver of humans. After the penetration of the parasite, the host organism react by activating complement- depending immune response. The aim of this study was to elucidate the influence of larval form of Echinococcus granulosus in the liver on the activity of antioxidative defense enzymes in the blood of patients before and after the surgical intervention. Methods. We investigated the activity of antioxidative defense enzymes: copper/zinc containing superoxide dismutase (CuZn SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and glutathione-S-transferase (GST) in the blood of patients before and after the surgical intervention in respect to the controls, clinically healthy persons. Results. Our results showed that the activity of the GSH-Px was significantly decreased in the plasma of the patients with echinocococal disease before the surgery in respect to the controls. The activity of GST was significantly higher in the blood of the patients after the surgery in comparison to the controls. Conclusion. Chronic liver echinoccocal disease caused significant changes of some antioxidative defense enzymes, first of all Se-dependent enzyme GSH-Px, which could be a suitabile biomarker in the biochemical evaluation of the disease. This work represents a first comprehensive study of the activity of antioxidative defense enzymes in cronic liver echinococcocosis in the patients before and after the surgical intervention in respect to the clinically healthy persons

    Antioxidant and Antimicrobial Activity of Some Tetradentate Schiff Bases and Their Cu(II) Complexes

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    Schiff bases, and their Cu(II) complexes, are known for their biological activity. In this work, antibacterial activity against Gram-negative strains of Escherichia coli, Pseudomonas aeruginosa and Staphylococcus pyogenes, as well as Gram-positive Staphylococcus pyogenes and Pseudomonas aeruginosa was studied, together with antifungal activity against Candida, Aspergillus, and Mucor strains. Also, technically simple, and rapid tests like ABTS, HORAC, and ORAC were used to investigate the antioxidant activity in order to compare obtained results with different type of tests
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